In bacteria [ 18, 25, 26] and nematodes [ 20], the global GC-content is the major factor governing variations in amino acid composition of their genes.
We propose vascular density and blood flow within a tumor as a primary evolutionary force governing variations in the phenotypic properties of cancer cells thus providing a unifying ecological framework for understanding intratumoral heterogeneity.
Our results demonstrate that inherent sequence characteristics govern variation in coverage and suggest that some of this variation, like GC content, should be controlled for in, for example, RNA-Seq and detection of copy number variation.
The lack of control over genetic background and environmental conditions, including previous exposures and olfactory learning, make it challenging to study the complex genetic architecture that governs variation in olfactory perception in human populations.
Similarly, the chemical properties of drugs might govern variations in the nature of seemingly identical mechanisms of drug resistance.
An optimal control law governing the variation of damping and stiffness is derived using optimal control theory.
Stepwise multiple regressions indicated that the most important variables governing the variation in the biological community composition were pond size, average annual daily traffic, metals, chloride, distance to the closest pond from study pond, dissolved oxygen, hydrocarbons, and phosphorus.
The method of characteristics is used to solve the partial differential equation governing the variation of the permeate flux and of the particle layer thickness and structure, with both time and axial position.
Chemical forms of copper, cadmium and lead in the rhizosphere of several plant species were investigated using rhizobox cultivation, sequential extraction and a set of specially designed experiments to examine dynamic changes in metal fractionation and bioavailability in the rhizosphere, and to experimentally evaluate the factors governing the variation in metal fractionation.
