Sentence examples for governing inflammatory responses from inspiring English sources

An understanding of which inflammatory pathways are targeted specifically by highly virulent F. tularensis will provide valuable information about bacterial pathogenesis as well as provide insight into the complex regulatory networks governing inflammatory responses during bacterial infection.

Thus, taken together, these data demonstrate that despite being well recognized as an autocrine/paracrine mediator, LTC4, via an intracellular cysLTR distinct from cysLT1R and cysLT2R, may also dynamically govern inflammatory responses as an intracrine mediator of eosinophils' PMD-mediated cytokine secretion.

Mechanisms governing the inflammatory response during sepsis involve crosstalk between diverse signaling pathways, but current knowledge provides an incomplete picture of the syndrome.

Mechanisms governing this inflammatory response have been shown to be complex and dynamic, involving cross-talk among diverse signaling pathways.

Three pathways related to innate immunity were more highly expressed in the vitamin D-deficient group: TLR signaling (gene set 64 and 65), a major pathway governing the inflammatory response to infection, and IL-1R pathway (gene set 55), which increases migration of leukocytes to sites of infection.

It is unclear which of these effects governs inflammatory cell signaling.

Our group previously reported MMP7 governs the inflammatory response through the shedding of syndecan-1 [4].

Our data indicate that a coordinated genetic program rather than single pathways governs the inflammatory response evoked by the cardiac surgery with CPB.

This heterogeneity forms, for example, the basis of a putative 'stromal address code'; differential expression of fibroblast cell-surface proteins and secreted cytokines results in differential recruitment of leukocytes, in turn governing the nature of the inflammatory responses in different tissues [ 18].

Lung injury promotes the expression of matrix metalloproteinase-7 (matrilysinilysin), which is required for neutrophil recruitment and re-epithelialization. MMP7 governs the lung inflammatory response through the shedding of syndecan-1.

Particular emphasis was placed on genes governing nutrient metabolism and stress and inflammatory responses.