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Such events also span multiple time domains from the fast molecular reactions governing gene expression to the slower cell cycle and division.
The regulatory networks governing gene expression can diverge significantly among different bacteria.
Epistasis (synergistic interaction) among SNPs governing gene expression is likely to arise within transcriptional networks.
We initially conducted a genome-wide screen for cis-trans epistasis governing gene expression.
The knowledge about mechanisms governing gene expression in tumor onset and progression appears essential for efficient therapies setting.
In these models, directed edges from TFs to their target genes represent transcriptional regulation, and constitute a hierarchical network governing gene expression [ 2, 12].
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It is also possible that in the co-culture situation production of secreted factors from the ligand-expressing cell may synergize with Notch ligand activation to govern gene expression, which may at least in part explain the difference between the "co-culture" and "immobilized" Notch signatures.
A group of regulatory events, referred to as epigenetics, govern gene expression without affecting the underlying DNA sequence.
Multi-protein assemblages known as enhanceosomes govern gene expression by local committee thus dictating regional transcription factor function.
RNA regulation is key to understanding the rules that govern gene expression regulation and epigenetic changes.
Combinatorial regulation can explain, in general, how a relatively small number of TFs can govern gene expression under diverse conditions.
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