Sentence examples for govern specification from inspiring English sources

In spite of numerous studies, the transcriptional network and the developmental cascades that govern specification and early differentiation of dopaminergic or serotonergic neurons reveal missing determinants, and are not yet understood.

Although these neuronal subpopulations reveal positional and developmental relationships, the developmental cascades that govern specification and differentiation of mDA or 5-HT neurons reveal missing determinants and are not yet understood.

Recent studies have delineated the signaling pathways that govern specification of mesodermal precursor cells into myoblasts and subsequently into differentiated myotubes (reviewed in ref. 79).

These results may suggest a general RA-mediated mechanism which governs specification of urogenital-associated phenotypes from pluripotent stem cell sources.

The developing compound eye of Drosophila has long been a model of choice for addressing this question by dissecting the cellular, genetic and molecular pathways that govern cell specification, differentiation, and multicellular patterning during organogenesis.

Functional analyses in future studies will embed these pathways into the growing knowledge of gene regulatory networks that govern early specification and morphogenesis.

For instance, if a neuron will be generated, genes that govern the specification and differentiation of that particular subtype of neuron during development—such as Delta-Notch signaling or pathways leading to subtype specification, axonogenesis, or synaptogenesis become active again.

MicroRNAs (miRNAs) have been implicated in governing lineage specification and differentiation in multiple organs; however, little is known about their specific roles in mammopoiesis.

Nonetheless, he postulated that the mechanism governing PGC specification must be the same in both amphibian lineages, with the different origins of the cells resulting from divergent morphogenetic mechanisms.

In addition, recent studies suggest that cell-intrinsic events governing the specification of human PGCs are also different from those in mice, at least based on the results of in vitro assays.

In order to understand this balance between healthy and pathogenic responses, we are interested in defining the transcriptional regulatory mechanisms that govern (1) Th17 cell specification from naive T cell precursors and, (2) Th17 cell effector plasticity during inflammation.