Sentence examples for gout into from inspiring English sources

Monomania, a 19th-century malady to which my 21st-century immune system had developed no defenses, had crept into my soul, like gout into a poet's foot, and spoiled it by degrees.

As Aaron S. Kesselheim and Daniel H. Solomon of Harvard Medical School reported in 2010, that's what turned colchicine from a traditional medication for gout into a branded monopoly for the firm URL Pharma, which put colchicine on the market as Colcrys.

To address this issue, we carried out another secondary analysis by separating patients with gout into treated and untreated subgroups.

Next, the expert panel performed a threshold identification exercise designed to assess the members' willingness to enrol 47 paper cases, based on having sufficient confidence that the individual has gout, into a Phase 3 randomised clinical trial of a new urate-lowering agent with unclear efficacy and safety.

We then divided the gout patients into four groups according to status of being treated and adherence at each calendar year: not treated, non-adherent (those with a PDC less than 20%), partially adherent (those with a PDC of 20%79%%) and adherent (those with a PDC of at least 80%).

The studies reporting association between HFCS-sweetened soft drink consumption and serum urate levels and gout in men took into account consumption of meat, seafood, purine-rich vegetables and total vitamin C, 8 10 suggesting that serum urate levels and gout risk are independently influenced by soft drink consumption.

Without treatment, episodes of acute gout may develop into chronic gout with destruction of joint surfaces, joint deformity, and painless tophi.

This classification criteria set will enable a standardised approach to identifying a relatively homogeneous group of individuals who have the clinical entity of gout for enrolment into studies.

A key insight into gout pathogenesis that has arisen from ultrasonography studies is the observation that MSU crystals are present in some people with hyperuricemia, but without clinical symptoms of gout.

First, the task was to develop criteria that would enable standardised assembly of a well defined, relatively homogeneous group of subjects representative of persons with gout, for entry into observational studies or clinical trials.

For gout, we took into account the 'double contour sign' (Fig.  1a) and/or the presence of tophi, defined as a non-homogeneous mass that could be hypoechoic or hyperechoic, surrounded by a small anechoic rim (Fig.  1b).