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To ascertain the representative GOs, a hierarchical cluster analysis was performed based on the similarity of annotated genes.
Subsequently, we used two approaches exploiting the ordinal nature of the GOS: a proportional odds logistic regression model and the sliding dichotomy approach.
Glasgow osteosarcoma (GOS), a tumour known to display intermediate sensitivity to both irinotecan and oxaliplatin was provided by the Research Centre of Aventis Pharma (Vitry sur Seine, France).
Using a predefined cutoff value of 33 ng/ml, NSE measurements were performed at least once in 231 patients and a 100% specificity was reached for unfavorable outcome, measured by the GOS a month after the event.
In addition to the six specific C. coli clade 3 GOs, a total of 18 extra GOs were found to be present in at least one genome of clade 3, but missing in the other C. coli genomes (Table 3).
Similar(54)
"It went a-begging.
— Go a bit mad.
I went a few times.
Pupils going a different shape.
History went a different way.
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