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There is good visual agreement between the optical (Fig. 6(a)) and ultrasonic (Fig. 6(b)) images.
The results show that the signal distribution provided by such radiation present a good visual agreement with the simulated dose and the phantom structures, with a clear detection of the changing morphological scenarios here studied.
The azimuthal power spectra of the three models are also in good visual agreement.
There is good visual agreement between the two models with periods of high activity being captured by the FTMM.
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The computed dispersion index shows good agreement with visual observation of synthetic images and mechanical properties of the model compounds.
It is evident that automated scoring of micronuclei by automated image cytometry using different commercially available platforms [e.g. Metafer (MetaSystems), Pathfinder™ (IMSTAR), iCyte® (Compucyte)], particularly for lymphocytes, is at a mature stage of development with good agreement between visual and automated scoring across systems (correlation factors ranging from 0.58 to 0.99).
Although Ki-67 proliferative activity assessed by the automated system was in reasonably good agreement with visual assessment, its prognostic value with respect to recurrence-free and cancer-specific survival was not as high as visual assessment.
In conclusion, the present study does show good agreement between visual and automated assessment of Ki-67 proliferative activity in invasive breast cancer, and that automated assessment of Ki-67 LI would appear to be comparable to visual Ki-67 LI.
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