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Peptides from natural sources are good starting material to design bioactive agents with desired therapeutic property.
With the aim of obtaining pharmacologically active compounds, we have envisioned that the benzimidazole scaffold could be a good starting material for the development of good MTB inhibitors.
These results indicate that ATA may be a good starting material for the design of a novel class of NA inhibitors for the treatment influenza viruses.
They had only blood serum available, which is not a good starting material, Koopmans says, and besides, once an animal has high levels of antibodies, "you don't expect much luck in finding the virus".
Thus, this makes them a good starting material for the identification of peptides with biological activities including ACE inhibition activity.
Indeed, only the HAWW_5 protein when non-denatured was able to interact with the vector, showing that it is properly folded, functional and might be a good starting material for influenza vaccine construction.
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31 Experiments in Gossauer's lab revealed Cd2+ complexes of pyropheophorbide a to be good starting materials for obtaining the desired [4,5]- seco-[4,5]-dioxo regioisomer as a main oxygenation product.
However, no improvement in selectivity whilst maintaining good conversion of starting material was observed.[ 22] Finally, variation of the phosphine ligand was undertaken.
Since most biomarkers used in clinical screening are blood based, it has been suggested that maternal plasma obtained in the first trimester could be a good source of starting material [116].
It is expected that high purity and good homogeneity of the starting material is beneficial for uniform device performance.
However, the standard procedure for cDNA microarray analysis requires 5 μg of good quality total RNA as starting material for each target preparation reaction.
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