Sentence examples for good reference genome from inspiring English sources

Resequencing and transcriptom analysis are necessary for high dance linkage map and a good reference genome.

Although AAF is designed for subjects without a good reference genome, studies on species with a reference will also benefit from AAFs computation efficiency and user-friendly pipeline.

The establishment of a good reference genome in model systems, and for the human genome, has provided the foundation for many of the studies reported in this mini-review.

Given good reference genome sequence data, many of the core analyses performed in ENCODE could be repeated on any organism - looking for DNA methylation marks using custom antibodies or chemical modification to separate the Me marks from the unmarked DNA, looking for open chromatin using DNAse1, or fully cross-reactive anti-modified histone antibodies to identify histone marks.

The success of this strategy is thus linked to the availability of good reference genomes for specific varieties and organisms.

Our results indicate that using an external reference combined with a good quality reference genome could produce a list of the miRNA expressed in a specific tissue.

For species without a good quality reference genome, like the brown trout, the quality and reliability of transcript expression analysis using RNA-seq are dependent on the quality of the de novo transcriptome assembly.

Therefore, successful application of RNA-Seq depends on the availability or the development of a good quality reference genome or gene catalogue [ 24], and both are lacking in many non-model species.

The current paucity of good reference mitochondrial genomes among angiosperms may be among the major setbacks preventing resolved mitochondrial phylogenetic hypotheses in many plant groups.

However, the analysis of transcriptome data produced by these technologies for organisms with limited genomic information still presents challenges because the sequenced fragments must be aligned against existing good quality reference genomes [ 27].

In a scenario where the size of the genome is not available any reasonably good estimate of the reference genome size is adequate for the purpose of computing the FRC, since the genome size is simply used as a normalizing denominator across all the assemblers to compare the contigs quality.