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Regarding the statistical methods employed, 14 studies performed the necessary statistical analysis for a good quality study.
One large, good quality study showed that a single dose of gentamicin caused a significant increase in the number of patients suffering from transient acute kidney injury (AKI).
The reported prevalence in one collaborative good quality study in Nigeria about 20 years ago among those aged >60 years was 2.3%.
Regarding L-carnitine supplementation, there is no good quality study nor expert consensus on its effectiveness [ 10, 56], data on prescription habits in France are lacking, and its use in other countries is heterogeneous.
Only one good quality study reported absolute blood pressure as an outcome, but pooling of four studies showed a significantly lower absolute outcome systolic blood pressure in favour of nurse prescribing: weighted mean difference −7.2 mm Hg (95% confidence interval −10.9 to −3.5).
Good quality study tables will be crafted with solid wood and wood is expensive, as is the labor that goes into making it.
Similar(54)
We found that many searches brought back very few good quality studies: we needed more large-scale randomised trials and well conducted systematic reviews to tell us about the effectiveness and safety of treatments.
In order to minimise this error, you have to amalgamate all the good quality studies to increase the population base of your work and bring in a variety of settings, thus ironing out any discrepancies.
There are anecdotal reports of improvement in muscle symptoms with administration of an over-the-counter supplement, coenzyme Q10, but benefits are not well documented via good quality studies.
Therefore the report advocates for conducting good quality studies, as described, going forward.
We were unable to get the heart rates of the pigs low enough to permit good quality studies on a 16-slice CT scanner.
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