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The synthesized Compounds were characterized by Melting point, Thin layer chromatographylnfra red, Nuclear magnetic resonance spectroscopy, etc. Almost all the synthesized Compounds possessed good activity as compared to the Standard.
Linezolid has also been shown to have good activity as compared to vancomcyin in Staphylococcus aureus bacteremia [ 14].
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Compounds, f1 showed good antioxidant activity as compared to standard by scavenging of nitric oxide radical and hydrogen peroxide, while f2 showed most potent antioxidant activity by scavenging of nitric oxide (Table 44, Fig. 12) [7].
The result evidenced that Sida urens is with acceptable levels of bactericidal activity and showed good antibacterial activity as compared with that of standard drug Gentamicin.
Compounds with significant pA2 values exhibited good anti-depressant-like activity as compared to the vehicle-treated group.
Novel compounds were obtained with good anticancer and antibacterial activity especially fluorinated pyridine derivative 4a and molecular docking study suggest good activity as mitogen activated protein kinase-2 inhibitor.
In forced swim test, the compounds with higher pA2 value exhibited good anti-depressant-like activity and compounds with lower pA2 value failed to show activity as compared to the vehicle-treated group.
One good example is Artemisia annua where whole leaves extract of this plant has exhibited better antiplasmodial activity as compared to its isolated compound, artemisinin [ 14, 15].
RE-Y exhibited higher activity as compared to silica alumina.
NF-κB activity is expressed as relative luciferase activity as compared to control cells.
The n-hexane, ethyl acetate and methanol extracts showed good activity compared to the other extracts.
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