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However, the more depolarized Vm of apical IHCs, and the consequently larger resting membrane conductance, made positively going responses to stimulation generally smaller than in basal cells.
The volunteers were asked to respond to green colored stimuli ("go" response) and to inhibit responses to red stimuli ("no-go" response).
Behavioural results revealed that individual differences in Go response time variability were a strong predictor of inhibitory success and that differences in mean Go response time could not account for this effect.
They had 1 second to trigger their go response after which any response was considered as a no-go.
Children earned five points for a fast "Go" response (faster than their "Go" practice mean RT) and two points for a slow "Go" response.
The Go response had to be entered in under 700 ms in order to be registered.
Mice reported the presence of a pole at a target position (the 'Go stimulus'; proximal) or in a distracter position (the 'No Go stimulus'; distal) by either licking (Go response) or withholding licking (No Go response).
The reward contingency was unchanged from these experiments, that is, digging in the single cup was rewarded in location 1 ("go response"), not rewarded in location 2 ("no-go response").
Greater points were awarded for a correct "Stop" that was preceded by a fast "Go" response (15 points) than a correct "Stop" that was preceded by a slow "Go" response (six points).
A Go response (button press) was required only on two of the five stimuli patterns; a noGo response (withhold button press) on the three other patterns.
Consequently, on reversal trials, a stimulus for which subjects had previously gripped (Go response) now instructed a no-grip response and vice versa.
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