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In addition to the goal of refinement of the current approach to DNT testing, there is another and more pressing driver of change in the science arena of DNT.
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The goal of the refinement process is to maximize the scoring function by following the direction of a few low-frequency normal modes.
Starting from low-resolution models generated by coarse-grained structure modeling or low-resolution experiments, the goal of structural refinement is to improve the quality of the structural models by driving the structure closer to the native.
The purpose of this study was to evaluate HOP implementation with the goal of informing HOP refinement and potential future HOP dissemination.
The goal of the annotation refinement was to minimize the impact of annotation inconsistency and improve the precision of 'unfixed ortholog' recognition.
As introduced in the previous section, the goal of interactive multigrid refinement is to reduce the local registration error of deformable registration methods.
The goal of the LO-refinement is to resolve a higher resolution structure of each rigid module.
One of the difficulties that goal-oriented requirements analyses encounters is that the efficiency of the goal refinement is based on the analysts' subjective knowledge and experience.
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Individual sessions each last 30 minutes and include assessment of existing goals, problem solving for barriers and relapses, goal refinement, implementation for appropriate referrals, and evaluation of progress towards long-term goals.
A key difficulty is that stakeholders typically convey their goals indirectly through intuitive narrative-style scenarios of desirable and undesirable system behaviour, whereas goal refinement methods usually require goals to be expressed declaratively using, for instance, a temporal logic.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com