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Further investigation in mechanism and risks associated with immune responses in human as well as a well-designed monitoring plan in clinical trials are essential to achieve the goal of efficacy and safety of the rAAV vectors in clinical trials.
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We conducted the current study with the goal of increasing efficacy of the prevention of migraine attacks using quetiapine as an additional (supplementary) medicine in patients suffering from Chronic Migraine [2] and already taking anticonvulsants.
Since its introduction in 1973, a number of different diclofenac-containing drug products have been developed with the goal of improving efficacy, tolerability, and patient convenience.
A variety of chemotherapies, targeted therapies, and immunotherapies since have been developed and approved for use in mCRPC, with the goal of improved efficacy outcomes when compared with docetaxel [[ 9]].
It essentially involves connecting a drug release (or injection) point to a predetermined site with the goals of high efficacy and safety via controlled drug release location, timing, dosage and transport.
Informed individualisation of treatment intensity should help us achieve our goals of improved efficacy and reduced toxicity.
If such studies continue to demonstrate a favorable safety profile, then it may be possible to combine A. paniculata extract (HMPL-004) with other drugs of known efficacy such as corticosteroids, azathioprine, and anti-tumor necrosis factor agents, with the goal of achieving synergistic efficacy without incurring synergistic toxicity.
With the goal of enhancing the efficacy of anti-angiogenic therapy, we are developing a novel radiopharmaceutical that is designed for VEGFR-mediated intracellular delivery of 177Lu [22].
This pilot project was designed to develop procedures for and test the feasibility of implementing Cognitive Enhancement Therapy (CET) in a group home environment, with a goal of maximizing treatment efficacy by augmenting social engagement in group CET sessions with ongoing social interaction.
Given the considerable promise of this method, further studies should explore use of different solvents (alcohol, lidocaine) with the goal of boosting CaCl2 efficacy at the well-tolerated 20% dose.
With a goal of improving vaccine efficacy in mind, whole genome comparisons were performed between phenotypic variants of Salmonella Enteritidis to find promising antigenic targets (Guard et al., 2011).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com