Exact(1)
The process appears to go on chronically as the same pattern is present in 12 m.o.o
Similar(57)
Go on, go on.
When over two-thirds of primary and acute budgets now go on the chronically ill, that's close to the holy grail of cutting spending without punishing the poor.
And until I read David Rees I didn't realize why it was that although I, too, relied on an electric pencil sharpener, it left me chronically unsatisfied: you can't see what's going on in there.
There is no obvious difference in the amount of viral adaptation at the first time-point between subjects that go on to become chronically infected and those who spontaneously clear the virus, although limited numbers here for each outcome restrict a more formal comparison.
Patients who go on to be chronically infected often do not lack a cell-mediated response initially, but there is evidence that the timing, persistence and functionality of the response are insufficient to control HCV [21,48,49].
It should be noted, however, that responses of similar breadth and magnitude to those affording protection from persistence in some patients have been seen in patients who go on to be chronically infected and there have been contrasting results when trying to correlate the magnitude of the intrahepatic cytotoxic T lymphocytes (CTL) and viraemia or outcome of infection [33,45,58].
Patients with hepatitis C virus (HCV) infection who are chronically infected may go on to develop cirrhosis and hepatocellular carcinoma.
We meet many people who are chronically sick or have sick children and say they can't go on living in this way.
About 15% of chronically infected patients develop cirrhosis and, eventually, 5% of these cirrhotic patients may go on to develop hepatocellular carcinoma (HCC) within 5 years [ 5, 6].
Firms that go on offering insurance must worry about things unrelated to their true business, such as whether a prospective employee has a chronically sick child.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com