Sentence examples for go dose from inspiring English sources
A phase II trial is currently underway investigating this approach with a GO dose of 9 mg/m2 per dose.
With the increase in GO dose, the toxicity reaction of the lung of mice becomes more and more severe.
As the cell culture day increased, the survival rate of cells decreased correspondingly, highly dependent on GO dose and culture time.
Secondly, antibacterial properties are in line with G and GO dose changes; 50~100 μg/ml GO concentration could balance biological toxicity and antibacterial ability better.
The effects of GO on mouse fibroblast cells depend on GO dose, and as shown in the study of Wang et al.[55], the effects also depend on the culture time.
The patient finally died in blast crisis after a cumulative GO dose of approximately 45 mg/m.
Doses go below doses that are common in CT angiography and compete with what is possible with the latest technology on dual source CT using prospectively triggered high-pitch spiral acquisition [88].
The selection of GO doses (0.75 mM and 1 mM) was made on the basis of a MTT assay performed on hMSC-TERT and on our previously published results on human skin fibroblasts [19, 20]. Figure 1 shows that GO-treated cells attained typical in vitro senescent cell morphology in terms of becoming significantly large, irregular, flattened, vacuolated, multinucleated and heterogeneous.
Patient #9 received three GO doses of 3 mg/m, which reduced the proportion of bone marrow blasts from 86% at baseline to 20% on day 28.
Two patients (#4 and #6) who received three GO doses of 3 mg/m2 (on days 1, 4 and 7) had no change in their bone marrow blast counts on day 15.
Examples include: go/no go decisions, dose and schedule selections, optimal trial designs and analysis, comparator differentiation, risk-benefit analysis, discovery target choices, hypothesis testing in in silico models, comparing drug candidate efficacy/safety profiles, predicting human doses, optimal combinations of compounds, and understanding the right patient population.
