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The results from photophysical property investigations indicate that all the compounds possess considerable two-photon activities, and one of these probes possesses the largest two-photon action cross section (Φδmax) value (OT1, 850 nm, ∼370 GM) compared with previously reported mitochondrial imaging agents.
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Further study showed that peripheral blood mononuclear cells co-cultured with irradiated normal bone marrow stroma generated increased numbers of CFU-GM compared with controls but failed to generate erythroid progenitors, providing evidence for an intrinsic defect in erythropoiesis.
Remarkably, the spleens of PHZ-treated knockout mice contained a greater number of both GMPs and CFU-GM compared with wild-type animals, indicating that the Ink4bKO animals in response to PHZ are not able to increase the number of MEPs and instead overproduce GMPs.
Statistical significance of differences in the GMs compared with the reference category for each parameter was assessed using the adjusted Wald test, which is a modified version of the F-test that, as implanted in Stata, takes into account the survey design characteristics of the data set.
Japanese consumers requested a 60% discount for GM noodles compared with non-GM noodles.
Fibroblasts under basal culture conditions express much higher levels of IL-6 and GM-CSF compared with AMs.
The high sensitivity to SGG shown by DBA/1 and DBA/2 mice may be attributable to differences of their regulation of GM-CSF compared with that in other mice.
BCG induced a >2 fold change in the expression of granulocyte colony stimulating factor (G-CSF), matrix metalloproteinase 1 (MMP1), guanylate binding protein 1(GBP1) and GM-CSF, compared with PPD.
The performance of Walktrap-GM is compared with two highly cited platforms developed to find network modules using gene expression data in interaction networks, jActiveModules[ 20] and Matisse[ 22].
As expected, cold stress showed a weaker influence on Gm Hsp20 expression compared with the heat treatment.
Surface transplants revealed an accelerated and enhanced angiogenic response of GM-CSF overexpressing cell lines compared with GM-CSF negative clones (Fig. 2B D), leading to a fourfold (42 days) higher amount of blood vessels within the tumor tissue (Fig. 2C) and fivefold (14 days) or twofold (21 days) higher amount of blood vessels in the tumor adjacent stroma (Fig. 2D).
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