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In this regard, in silico metabolic modeling and analysis allow us to predict the cellular behaviour and metabolic states globally upon various environmental/genetic changes (Lewis et al. 2012).
In this study, western blot and immunofluorescence data demonstrated that H3K9Ac was decreased and H3K9Me2 was increased globally upon MSC osteogenic differentiation (Figure 2A and B).
Both H3K9me3 and H3K27me3 were previously reported to change globally upon cellular senescence in human primary fibroblasts.
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There is solace in the fact that 140 world leaders came to the United Nations in September to rededicate themselves to the Millennium Development Goals, the globally agreed-upon targets to fight poverty, hunger and disease.
With the International Classification of Functioning, Disability and Health (ICF), we can now rely on a globally agreed-upon framework and system for classifying the typical spectrum of problems in the functioning of persons given the environmental context in which they live.
A recent bilateral agreement between the U.S. and China was meant to encourage more ambitious pledges, but it is hard to imagine uncoordinated voluntary and bilateral pledges adding up to anything close to what would be accomplished under a globally agreed-upon framework.
⇨ Contextual changes in the rehabilitation field revealing an understanding of the importance of properly classifying and recognizing the different health problems that a patient is confronted with, using the International Classification of Functioning, Disability and Health (ICF), a globally-agreed-upon framework of the World Health Organization.
The resolution states that the company "should analyze the impacts on ExxonMobil's oil and gas reserves and resources under a scenario in which reduction in demand results from carbon restrictions and related rules or commitments adopted by governments consistent with the globally agreed upon 2 degree target".
Yet physicalists need not maintain that everything strongly globally supervenes upon the physical.
Thus, the globally agreed upon safety assessment regime concerning conventional hybrids is non-rigorous.
10.7554/eLife.07378.008 Figure 2. Heterochromatin-embedded genes are globally perturbed upon HP1E-depletion.
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