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To investigate whether sex-biased gene expression in mammalian brain is globally regulated or locally regulated in diverse brain structures, and to study the genomic organisation of brain-expressed sex-biased genes, we performed a large scale gene expression analysis of distinct brain regions in adult male and female mice.
Although the mechanism for this regulation is uncertain, other globally regulated genes, including circadian and clock-controlled transcripts, cycle in different phases in brain regions outside of the suprachiasmatic circadian pacemaker making the cycling of Fabp7 unique.
"It would be nice to live in a world of unicorns where they could come up with an international framework that globally regulated government support," said Richard L. Aboulafia, an analyst with the Teal Group, an aviation consulting firm in Fairfax, Va.
Furthermore, transcriptome analyses revealed that alternative splicing was globally regulated by CELF1 in HeLa cells.
Currently, maritime safety is globally regulated by internationally agreed prescriptive rules, which are usually revised in reaction to accidents.
By virtue of adding a power integrator technique, an adaptive output-feedback controller is designed to render that the closed-loop system is bounded in probability, and the state of switched stochastic nonlinear system can be globally regulated to the origin almost surely.
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In particular, we explicitly design a universal output feedback controller which globally regulates all the states of the uncertain system while maintaining global boundedness of the closed-loop system.
Here, we highlight how these factors promote mRNA degradation to globally regulate both host and viral gene expression.
Bacterial 6S RNAs globally regulate transcription by binding RNA polymerase (RNAP) holoenzyme and competing with promoter DNA.
We design both a nonlinear feedback controller and a linear one which globally regulate the closed-loop system states to a given point.
Using the idea of universal control, we explicitly construct a universal-type adaptive output feedback controller which globally regulates all the states of the nonlinear time-delay systems.
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