Exact(4)
Further investigation of the Brassicacae expressed sequence tag (EST) databases using tBLASTn showed that none have homologues to QTRT1 or QTRDT1, showing that Q is probably globally absent from this phylogenetic order.
However, the relative importance of MyD88 within the CNS compartment compared with infiltrating peripheral immune cells was uncertain, since prior studies utilized MyD88 KO mice where this adaptor was globally absent.
Although our previous report demonstrated an essential and non-redundant role for MyD88 in eliciting an innate immune response during brain abscess development (Kielian et al., 2007), it remained unclear whether MyD88 expression was more important in CNS-resident compared with infiltrating immune cells since the molecule was globally absent in KO (knockout) mice.
This issue could not be resolved in our previous study since MyD88 was globally absent in MyD88 KO mice and the fact that the brain abscess model is complicated by the involvement of both activated CNS-resident and infiltrating immune cells both of which express this adaptor molecule (Kielian, 2004; Stenzel et al., 2005; Kielian et al., 2007).
Similar(56)
Stillbirths were not included in tracking progress on the Millennium Development Goals (MDGs) and have received little recognition for intervention strategies and programs globally; stillbirth targets are absent from the Sustainable Development Goals.
Biochemical insight can come from cataloguing globally or locally missing genes, i.e. those that encode enzymes for which a gene has never been identified in any species or is absent in certain species [ 36- 38].
Despite the important contribution of eclampsia/pre-eclampsia to perinatal and newborn deaths, it has—for the most part been absent from strategies elaborated globally to try to reduce the burden of such deaths.
On the one hand, some globally or locally conserved CYP families are absent in certain species.
Only detection calls, coded as 0 for absent or 1 for present, were used to globally compare our KL data to the BXD data.
A biochemical analysis confirmed that srf-3 mutants are globally deficient in galactosylation [36], but the specific glycoconjugates that are absent or aberrant are not known.
We show the existence of a globally stable steady state, and a threshold that determines whether a pathogen is either absent from all patches, or endemic and present at some level in all patches.
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