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The global substantial reduction in the prevalence of vaccine preventable diseases makes parents have little or no experience with such diseases, and as a result, the benefits of vaccination and the risks of not vaccinating are not appreciated as much as they were in 20th century.
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At the global level, substantial progress has been made in dragging people out of destitution, and extending their lives.
If, on the other hand, we face a prolonged global recession, substantial enough to blunt these price pressures, fiscal contraction will make the burden of funding government debt intolerable.
In its note, Capital IQ said: "We think FB has considerable competitive advantages in the social media segment, associated with its global brand, substantial user base, high levels of engagement, and considerable access to valuable user data and information.
In some versions of the snowball Earth scenario, even the surface of the oceans was completely frozen, blocking the release of oxygen into the atmosphere by ocean-dwelling phytoplankton, thereby potentially affecting the timing and pace of evolution.Yet some climate models have hinted that even in this death grip of global cold, substantial parts of the ocean remained open water.
While the rate of children at work is on the decline worldwide, child labour remains a substantial global challenge.
This appeared to contradict surface temperature measurements from thousands of thermometers around the world, which when combined together, indicated substantial global warming.
Haemoglobinopathies constitute the commonest recessive monogenic disorders worldwide, and the treatment of affected individuals presents a substantial global disease burden.
"Obesity" equals disease to medical professionals, while in the world of public health it is a raging epidemic with substantial global mortality.
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver dysfunction and a significant global health problem with substantial rise in prevalence over the last decades.
Art business schools say they see these developments as new opportunities in an already substantial global market.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com