Sentence examples for global proliferative from inspiring English sources

The patient was diagnosed with active, diffuse, global, proliferative glomerulonephritis class IV-G lupus nephritis.

Therefore, a very active diffuse global proliferative lupus nephritis (WHO IV B, ISN/RPS IV-G (A)) was diagnosed.

This suggests that Wnt signals may influence discrete cell populations rather than act as a global proliferative regulator within the crypt.

In contrast, the global proliferative response of T cells to TCR stimulation could be recovered, at least in part, in the absence of persistent antigens.

To distinguish if the Wnt signal conveys a restricted rather than global proliferative response within the intestinal crypt, intestines from Wnt-reporter mice were co-stained with antibodies to β-gal and the proliferation marker Ki67, which designates cells undergoing late G1, S, G2 or M phases of the cell cycle.

These global anti-proliferative effects of EGC upon IEC have to be associated with the EGC-induced modulation of genes that would tend to be pro-proliferative, although these are clearly in reduced numbers.

Thus, while increases in Ad5-specific CD8+ T-cell frequencies were observed in both baseline Ad5 seronegative and seropositive subjects following vaccination, sustained changes or global effects on the proliferative capacity of CD8+ T-cells were not found.

Our results represent a unique example of the extremely complex effects of steroid on target tissues, and emphasize the importance of a global approach when studying the proliferative effects of estrogens.

For the second time a kidney biopsy was performed and showed a mostly global sclerosing but also extracapillary proliferative glomerulonephritis again in combination with a membranous nephropathy (detailed in the legend of Figure 2).

Several markers have been proposed as predictors of the radio- and chemosensitivity of rectal cancers, including Bcl-2, Bax, epidermal growth factor receptor (EGFR), cyclooxygenase 2 (COX 2), microsatellite instability (MIS), mismatch repair (MMR) genes, Ku-70, Ki-67, vascular endothelial growth factor (VEGF), apoptotic rate, proliferative index, and global gene expression [ 5, 17].

In doing so, they provide further proof that maintenance of intrinsic cellular polarity can effectively counteract the devastating proliferative defects associated with mutations in global signaling molecules such as Ras.