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The hub vulnerability hypothesis would predict that an acute severe global insult would cause greater structural and functional damage to hub regions than to non-hubs.
Hence, it might seem surprising that such a global insult has cognitive effects that closely match those seen after very selective perirhinal cortex lesions in rats.
TRX reflects both inflammation and oxidative stress, two major determinants of severity of post-cardiac arrest syndrome and could be considered as a potential marker of the global insult.
The injury to the kidneys stems not only from oxygen deprivation and ischemic tissue damage, but also from the increased workload imposed on the kidney to amend the changes to acid base and electrolyte levels which occur with the global insult of hypoxia [ 115].
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Yes, both are shameful, but Abu Ghraib was a day at the beach compared to what Al Qaeda and its Sunni jihadist supporters have been doing in Iraq, yet none of their acts have become one-punch global insults like Abu Ghraib and Guantánamo.
We hypothesized that the global metabolic insult of TD was modified by EtOH, which provides significant metabolic energy independent of glucose (Fig. 13).
Thus, alcoholics consuming EtOH to levels that increase blood acetate providing metabolic energy may be protected against the TD-induced global metabolic insults, which primarily disrupt glucose metabolism (Fig. 13).
Hemorrhagic shock/resuscitation can be viewed as a global ischemia/reperfusion injury insult [ 3].
More direct evidence for hub vulnerability is required; this might include experiments in which a global (uniform probability) insult is administered in animal models.
This may reflect the fact that most of the damage measured by S-100B elevation is related to the primary global hypoxic-ischemic insult, rather than temperature-modifiable reperfusion injury.
He has preached that global warming is a insult to the Creator.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com