Sentence examples for global decreases from inspiring English sources

Furthermore, Deplus and colleagues showed that TET2 and OGT co-localize at active promoters marked by H3K4me3 through a direct interaction with host-cell factor 1 (HCF1) and that knockdown of TET2 leads to global decreases of H3K4me3 and GlcNAcylation (Deplus et al., 2013).

This result extends our earlier work demonstrating global decreases in H3-K9 methylandon and H3/H4 acetylation in bulk chromatin in the nervous system and in cell lines upon Myc loss of function [56].

In agreement with this, global decreases in H3K4me3 levels occur during retinoic acid (RA -induced diffeRA -inducedof mouse ES cells [ 47].

First, reductions in central retinal artery blood flow may be due to global decreases in retrobulbar blood flow from the ophthalmic artery and its branches.

These mutations were associated with global decreases in H3K36me3 levels in HGGs harboring either missense or truncating mutations in SETD2, suggesting loss-of-function (Fig. 4) [ 20].

Alterations in miRNA biogenesis machinery may also contribute to global decreases in miRNA expression, which also correlates with poor patient outcomes [1], [2], [6].

Insecticide treated bednets and anti-malarial medicine have already led to a 37% global decrease in malaria cases since 2000, and a 60% decline in the malaria mortality rate.

When we look at how physical activity has changed over the past 50 years, there has been a global decrease in physical activity and an increase in sedentary behaviour (time spent sitting).

A global decrease on spectrum sharing efficiency and usage fairness.

Also, another study indicated a global decrease in metabolism of CNS [10].

A global decrease was observed in the DA content along with an increase in MAO activity.