Sentence examples for global blockade from inspiring English sources

Remarkably, global blockade of activity with tetrodotoxin (TTX) interfered with the ability of single cell activity deprivation to slow down terminal dynamics suggesting that differences in activity levels among neighboring synapses promote synaptic remodeling events.

Also various infection models suggest a different outcome of global blockade of IL-6 as compared to selective IL-6 trans-signaling inhibition.

Interestingly, depending on the animal model used, global blockade of IL-6 signaling by neutralizing monoclonal antibodies and selective blockade of IL-6 trans-signaling can lead to different consequences.

While global blockade of CCL5 receptors using Met-CCL5 (Veillard et al, 2004) and CCR5 deficiency are associated with reduced atherosclerotic lesion size, CCR1-deficiency (somatic or in BM) was shown to exacerbate plaque formation (Braunersreuther et al, 2007).

A similar conclusion was reached recently by Whitehead and colleagues, who reported a "global blockade" of the AHR signaling pathway in a different population of PCB-tolerant killifish using a different microarray technology [ 68].

In contrast, in a sepsis model induced by a bolus injection of LPS, both, global blockade of IL-6 signaling by neutralizing monoclonal antibodies and selective blockade of IL-6 trans-signaling proved effective in preventing the death of the animals [ 5].

For it to succeed, it needs to win the Palestinian people's hearts and minds, which the new Palestinian government hopes to do by governing with transparency, breaking the global economic blockade and beginning serious negotiations with Israel.

The only sure way to nip the bug before it blooms is to blockade global trade and travel.

9, 10 However, long-term global NF-κB blockade may alter immune responses or cause cancer.

However, the major hurdle here is to overcome the global IL-6 blockade caused by these drugs.

We could recently show that inhibition of IL-6 trans-signaling was beneficial in a caecum ligation puncture model whereas global IL-6 blockade showed no benefit in survival of the animals [ 4].