To compare the dispersal of sporozoites gliding in avascular tissue to those gliding in proximity to vascular structures, the MSD of the two populations was plotted over time.
In quite all the experimental studies, performed after surgical procedures for tendon injuries or in the treatment of chronic tendinopathies, using different hyaluronic acid compounds, positive results (reduced formation of scars and granulation tissue after tendon repair, less adhesions and gliding resistance, and improved tissue healing) were observed.
As previously shown (Rink et al., 2009), IFT88 RNAi) animals lost their cilia-dependent gliding ability, developed massive tissue edema and had severely shortened cilia.
The gel retains all of the properties of HA but enhances its viscoelastic properties and acts as a tissue lubricator, which aids gliding [8].
The articular chondrocytes are the only cell population present in the adult hyaline cartilage, the avascular, aneural tissue responsible for a smooth gliding of articulating surfaces.
The properties of the tendon surface that enable gliding and define the boundaries of the tissue are poorly understood.
Imaging TRAP-VAL sporozoites, we find that their slow gliding speed significantly decreases the volume of tissue explored, which likely results in reduced ability to encounter blood vessels.
Whereas this part of the knee is biomechanical more affected by static loading and weight bearing, the patella cartilage tissue is more loaded by gliding under pressure over the trochlea surface during walking.
Thus efficient gliding might be more relevant for migration in tissue or through cells than for invasion.
In the US, the most widely taught and practiced style of relaxation massage is Swedish massage [ 1, 3], which employs five basic strokes: effleurage (gliding), petrissage (kneading and lifting), friction (moving the tissue layers underneath the skin), vibration, and percussion.
