This regulon is controlled by the transcription factor MetJ which represses genes involved in methionine biosynthesis and transport [ 1- 4]. Figure 1 shows various metabolic pathways involving methionine and Table 1 gives the functions of the genes.
Given the function of SMAD4 protein, a possible involvement of a non-functional TGFβ pathway in conferring resistance to anti-EGFR moAbs might be suggested.
Additionally, urban freight transport was not considered within any of these roles, despite the inherent need for deliveries given the function of the building.
Another sense in which it is unreasonable is that it ignores similarities and differences—here in health status between persons which, given the function of health care, ought to be relevant to establishing its reasonable distribution.
High tells Gangleri (earlier in the book described as King Gylfi in disguise) that Hlín "is given the function of protecting people whom Frigg wishes to save from some danger".
Expression in the spleen is hardly surprising given the function of spleen in the immune defence.
Given the function of the encoded protein, a LAAO enzyme, such restriction of protein expression makes sense.
Given the function of aurora B kinase, we examined whether there was an association between expression levels and genetic instability.
Given the function of FoxP3, we speculate that it confers a survival advantage on FoxP3-positive patients.
