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Given this specificity and that most KLKs require an enzyme with trypsin-like specificity for activation, it is not surprising that KLK activation cascades can occur in many tissues [ 13, 39, 40].
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Given this high specificity, its clinical application as ancillary diagnostic test or prognostic biomarker is promising.
Therefore, given this cellular specificity, targeted proteomic approaches can allow the detailed examination of cellular organelle regulation.
Given this taste cell specificity and the fact that both patients and normal subjects expressed δ-ENaC in their fungiform papillae, we conclude that even if it has a role in sour taste, it still plays an additional role in the taste bud, most likely as a receptor for saltiness.
Given this very high specificity, patients classified as being "at risk" (> 0.2 mm of migration between one and two years) are highly likely to suffer from clinical loosening at ten years.
Given this range of specificity and the corresponding NPVs (0.96 1.00), plus the identification of alcohol use factors associated with an incorrectly classified positive EtG fingernail test for increasing-risk drinking (number of drinking days and number of heavy drinking days in the past 12 weeks), the potential of EtG in fingernails as a quantitative indicator of alcohol use may hold promise.
Given this moderate to high specificity in the detection of MPNSTs, use of PET/CT has been recommended for biopsy planning.
Given this heterogeneity in the specificity of PFT and PGGT1 for certain CaaX proteins, deconvoluting the complex roles of protein prenylation in negative regulation of ABA signaling, meristem development, and other fundamental processes poses a significant challenge.
However, it was not clear how these proteins might have been eluted following TEV protease cleavage given the specificity of this protease.
Given the specificity of all antibodies used in this study we do consider this interaction to be genuine.
Given the specificity observed for SH2 domains in this study, the likelihood of a random sequence encoding an SH2 domain ligand appears rather limited.
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CEO of Professional Science Editing for Scientists @ prosciediting.com