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The detection of these lesions by smear examination was not reliable, given the wide expression pattern.
14 Given the wide expression of NKCC1, systemic administration of drugs that target it will influence a wide spectrum of tissues throughout the organism.
Study of additional families is warranted for better understanding of the phenotypic spectrum of this disorder given the wide expression of the LTBP3 gene.
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In the family of the FXTAS case, premutation-transmitting females presented a history of psychiatric symptoms, suggesting that, given the wide phenotypical expression of the premutation in females, neuropsychiatric surveillance is necessary.
Given the wide range of expression values, we categorized the tomato HAGs in three groups of low, middle and high expression.
Given the wide range of expression in autism and related disorders, there is no one-size-fits-all intervention.
Given the wide range of expression values, we categorized the tomato HDAs in three groups having low (see Additional file 4A), middle (see Additional file 4B) and high expression (see Additional file 4C).
DOI: http://dx.doi.org/10.7554/eLife.01630.007 Given the wide range of protein expression levels, the bulk of protein abundance in NB4 cells results from the expression of a relatively small number of proteins, as is shown in a cumulative protein abundance plot.
Given the wide fluctuation of mHLA-DR expression data, ratios were calculated between values for two points in time, namely days 3 and 4/days 1 and 2 and days 5 and 6/days 3 and 4. The slope of mHLA-DR expression at days 3 and 4 showed a highly significant statistical difference between non-septic and septic patients (1.44 ± 0.53 versus 0.83 ± 0.43, respectively; P < 0.0001) (Table 1).
Thus, brain circuits are likely to have evolved to decode expression signals fast and efficiently, given the wide range of viewing conditions in which facial expressions are typically experienced.
Modeling human disc degeneration with a reliable and reproducible animal model is an important step toward further characterization of disc degeneration given the wide inter-individual variation in gene expression, which limits studies on human tissue samples.
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