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Given the substantial challenges associated with characterizing and quantifying ENMs in soils and sediments, little research has been conducted to date on the homogeneity of ENMs in these media.
Given the substantial challenges for quantitative structure-based predictions of conformational exchange linebroadening effects, the degree of correlation between the predicted and observed linebroadening in the 80′s loop of FKBP12 suggests strongly that Gly transiently adopts a negative ϕ torsion angle when that residue is in a trans-peptide configuration.
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Given the significant challenges associated with adding a writing course into an already packed curriculum, the payoffs need to be substantial to justify the effort by both faculty and students.
Given the substantial range of rights and underlying goals expressed or implied in the CRPD, it is a challenge merely to devise a collection of targets that span the full scope of the CRPD.
22 Given the substantial burden of cancer, considerable research has focused on the impact of patients' and partners' coping with cancer challenges on their health and well-being.
The courts have given the executive branch substantial but not total deference, often holding that the president has the authority to designate enemy combatants but allowing those detained to challenge the factual basis for the administration's determinations.
Given the magnitude of the challenges I just presented, the key question is: how can governments manage public finances to deal with these daunting long-term challenges, while also coping with the substantial near-term risks and uncertainties?
Civil liberties groups say the proposed renewal would do too little to let targeted people challenge national security letters and types of subpoenas that give the FBI substantial latitude in deciding what records -- including those from libraries -- should be surrendered.
Often, one of the most substantial challenges, however, is raising capital for your business.
However, deep sequencing technologies have generated hundreds of thousands of reads with large amounts of data, which give us substantial bioinformatics challenges to mine the hidden biological significance.
However, next-generating sequencing technologies have produced hundreds of thousands of short reads with large amounts of data, which give us substantial bioinformatics challenges to discover the hidden biological significance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com