Sentence examples for given the significant variability from inspiring English sources

Given the significant variability in testosterone (T) from a physiologic and assay perspective, a thorough understanding of factors affecting T values and study methodology is essential to interpret reported study outcomes appropriately.

The Process Subcommittee decided to use the ISPOR recommendations as a starting place for the consensus process rather than to conduct additional literature reviews given the significant variability in methods already noted.

However, given the significant variability in resulting prevalence estimates, and the variability in methodological features outlined earlier, the estimates should be considered with caution.

Given the significant variability of cost and lack of cost transparency in the US health system, 17 21 decision support tools that show total costs and patient out-of-pocket costs could be a means to empower physicians and patients as informed healthcare consumers.

In particular, given the significant role of genetic variability in determining how patients respond to pharmacotherapy [ 12], validated genetic and genomic tests may soon be available for guiding the pharmacotherapy of a variety of common diseases including asthma [ 13], hyperlipidemia [ 14], hypertension [ 15], and various cancers [ 16].

Given the significant covariability between these indices and the global warming trend, however, the extent to which observed changes are due to natural variability rather than anthropogenic climate change cannot yet be conclusively determined.

Given this significant variability in the MAE values, one could wonder whether just a subset of the models having relatively small MAEs (e.g., values below a certain threshold) should be used for predicting the tissue log Kt:p values to be used as descriptors in the Vss-target dataset, whilst other tissues' log Kt:p values (with large MAEs) should be ignored.

This may or may not be true because of the heterogeneous nature of the composite (consisting of fibers and matrix and interface), and the significant variability which gives rise to random spatial variation in the properties.

Figure 1 shows the temporal pattern of changes in HR, SDNN, and rMSSD over the 13-day summertime exposure period, providing both daily means and 30-min data to illustrate the significant variability, both within a given day and across days.

However, it has been difficult to compare results from these studies given significant variability in key methodological issues.

This meta-analytic documentation of a conclusive, but small, relation between TID and cognitive function in a large pediatric sample is significant given the "noise" and variability present in most clinical research studies.