Sentence examples for given the proliferative from inspiring English sources

Given the proliferative role of Myc in our model and our data suggesting HSPC111 interacts with RNA in the nucleolus, we questioned whether HSPC111 might play a role in Myc's effects on cell cycle progression.

Given the proliferative effect of EBI2 8, as well as the reported role of EBI2 in recruitment of immune cells to tumors, a potential role of EBI2 in EBV- and non-EBV-mediated cancers should be explored.

Given the proliferative role of Myc in our model and the well characterized link between RNA biosynthesis and cell proliferation [ 30], we asked whether HSPC111 could recapitulate this aspect of the Myc phenotype.

Transplantation of mesenchymal stem cells (MSCs) is a promising strategy given the high proliferative capacity of MSCs and their potential to differentiate into cartilage-producing cells - chondrocytes.

Given the greater proliferative capacity of HIV-specific CD8+ T-cells of LTNP/EC compared to progressors, it is critical to additionally measure cytotoxic capacity on a per-cell basis.

One approach started with the long standing observation that the physiology of the tumorstroma interface appears to have much in common with that of a wound that is in the healing process, given the potent proliferative, invasive, and angiogenic stimulations in both contexts.

Given the anti-proliferative properties of CBD, we hypothesized that this compound could exhibit therapeutic potential in the context of liver fibrosis by preventing proliferation of activated HSCs.

Given the very low proliferative activity in the ventricular wall of the 3rd ventricle [11] the risk of mistaking 3rd ventricle precursor cells as hippocampal was further diminished.

However, since we did not observe any hepatocyte proliferation at the histological level, and given the measurement of proliferative cell nuclear antigen (PCNA) (data not shown), our results indicate that the pro-apoptotic branch of the MAPK pathway predominated in BaP-treated Xenopus.

Although the effects of aging on human HSC have not been as extensively studied, human HSC function also appears to be affected by aging given the observation that the proliferative potential of human HSC declines with age [ 48].

As such, the tissue-specific response of telomeres should be investigated, with specific consideration given to the proliferative demands placed on the tissue by the exercise stimulus and the antioxidant capacity of the individual tissues.