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Given the indispensable contribution that they make, it seems perverse that the role of subs has been questioned, albeit mainly from those more interested in the cost of everything than the value of anything.
Given the indispensable function of the β -chain in IL-2 signaling of T cells, diminished expression may contribute to disturbed immune homeostasis in AAV.
Given the indispensable role of satellite cells in muscle regeneration (Sambasivan et al., 2011a; von Maltzahn et al., 2013), the behavior of satellite cells, especially their replicative and differentiation capacity, determines the progression of muscle dystrophies.
Given the indispensable roles of regulatory T cells in immune balance and tolerance, a great deal of effort has been focused on elucidating Tregs identity, heterogeneity, stability and function.
Nevertheless, given the indispensable role for BLyS in B-cell development [ 9, 10], a certain threshold level of BLyS is required to permit any antibody responses (including autoantibody responses).
However, given the indispensable role PSY genes play in the carotenoid pathway as the first committed step, we have now also characterised the apple PSYs by assessing any overlapping or specialized roles they might have in fruit, from enzymatic function, protein localization and transcript levels.
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PACIFIC GROVE, CALIFORNIA An international group of scientists, ethicists, and governance experts meeting here this week has agreed that research into large-scale modification of the planet is "indispensable" given the "threats" posed by climate change.
As it turns out, "Visions of Jazz" is the finest unconventional history of jazz ever written -- a brilliant, indispensable book, comprehensive enough given the certainty that a total history of jazz at this point, the century mark, invites a shallow inclusiveness.
Given the rapid expansion of communication technology, devises such as GPS are now indispensable gadget.
Given the many challenges the new chief will face, a broad range of experience is indispensable.
Given the high prevalence of vitamin D deficiency in Iran, effective solution to overcome its consequences seems indispensable.
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