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Given the constrained nature of health care spending, careful consideration of costs relative to the clinical consequences of alternative treatments should support decision making.
The tool is SpamAssassin, and it's lately been making the rounds among companies and organizations looking to gain control of their spam intake without spending a huge pile of money which, given the constrained nature of IT budgets these days, should make the program pretty popular.
Given the constrained resources in middle-income Thailand, and the possibility that psychologically stressful work is becoming more widespread, our results on psychological distress are of particular concern.
Given the constrained and in some cases declining resource base and the consequent need to significantly increase nutrient and water-use efficiencies, as well as the need to reduce input costs more generally, it seems likely that GM will become increasingly standard technology in crop improvement programmes, complementing ongoing efforts in conventional breeding.
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Given the constrains of limited exposure, this study attempted to demonstrate that dexamethasone, which is the backbone of most therapeutic regimens for multiple myeloma, reduces the plasma concentration of panobinostat, 40%% of which is metabolized by CYP 3A4 enzyme.
Given the constrains pose by time, and the relatively low rate of physician adoption of some clinical guidelines in general [ 10- 12], the extent to which GPs document recommended screening is not well understood.
Given the temporally constrained nature of the BOLD signal, fMRI studies are of limited value in this endeavour.
Given the tightly constrained promoter position relative to the TSS (usually between 7 to 10 nucleotides) promoter identification is straightforward once the TSS has been experimentally determined.
Given the highly constrained resources for health promotion, it is essential for decision makers to require information on the costs and cost-effectiveness of the interventions.
The navigation system becomes a key issue given the safety constrains of the heavy load to be transported in the complex scenarios, such as the reactor building.
Given the tight constrains in the definition, conserved TFBSs were scored in much smaller numbers than in the Clover analysis.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com