"given the central importance" is a correct and usable phrase in written English.
You can use it when you want to emphasize the importance of something. For example, "Given the central importance of the issue, it is crucial that we find a solution quickly."
It said: "The damning verdict by the commission on how tax was applied in the Apple case leaves the [Irish] government with little option but to lodge an appeal, given the central importance of foreign direct investment to our economy..
The victims were generally children, who ought to receive special protection; the abusers were often repeat offenders, who should have been stopped; and criminal prosecution of the priests was made all but impossible given the central importance of the victim's testimony in rape and other sexual abuse cases.
The second claim of lesbian feminists, given the central importance of heterosexuality and marriage (then confined to male-female relationships) to the maintenance of male supremacy, was that lesbian individuals and relationships presented a profound challenge to the social and economic order.
Given the central importance of security of some external resources, it is implausible that agents have no power to appropriate without the consent of others.
Given the central importance which it later attained, it is surprising how late supposition was in being identified as one of the properties of terms.
Given the central importance of CD4+ T cells in containing Mtb infection, the occurrence of a progressive primary TB in HIV/AIDS patients is conceivable.
Greater recognition was given to the central importance of the teacher in making an impact on classroom learning, as the teacher came to be seen as the ultimate implementer of educational policy.
Obtaining a clear understanding of how each pathway contributes to substrate recognition by the proteasome is of considerable importance given the central role of the UPS in regulatory biology and the clinical significance of the proteasome as a target for cancer therapy [ 28, 29].
Given the central role of monocytes in the immune response and the importance of coordinating activation in specialized microenvironments [52] we investigated the effect of PMA stimulation on CD86/CD11b expression.
It is difficult to overestimate the symbolic importance of a Colombian president entering the debate with such force, given the central role drugs have played in his country's recent bloody history.
Given the central role of SRs to this process, we conducted antibody blocking experiments to determine the relative importance of CD36 and SR-A in db/+and db/db PerMΦs.
