Sentence examples for given the broad expression of from inspiring English sources

Given the broad expression of defensins and the general importance of PIP2 for cellular physiology, this work should be of great interest to the diverse readership of eLife.

Given the broad expression of FGFRs and their key role in development and physiology, toxicity issues are to be expected from FGFR inhibition.

Given the broad expression of miR-9, the other reviewers wondered about phenotypes at the level of the whole animal resulting from widespread changes in dendritic and axonal arborization.

Given the broad expression of Megf8 in a wide range of tissues during development, we next asked whether these defects, and in particular the TG defect, are due to a cell autonomous function of Megf8 in sensory neurons.

Given the broad expression of Gr66a gustatory receptor in most bitter-sensing neurons (Mitri et al. 2009; Isono and Morita 2010; Weiss et al. 2011), we predicted that Gr66a -expressing sensory neurons would mediate at least the positional aversion response.

Genetic experiments demonstrating that piwi expression in ISCs (or possibly terminal filament and cap cells given the broad expression of the Gal4 driver utilized) can rescue Btk29 mutant defects in germ cell differentiation clearly indicate an important role for piwi in this process (Hamada-Kawaguchi).

Given the broad expression domain of Smarcd3 mRNA and our Smarcd3-F1 ::lacZ reporter lines, we sought to define an enhancer fragment that might uniquely label early cardiac progenitors.

Similarly, given the broad expression and basic cellular functions of wild-type huntingtin, it seems likely that mutant huntingtin may affect the aetiology of other diseases.

The exact question we ask is: can one come up with the expression rank in the OO system given the expression rank in WBC? Or, even more broadly, given the broader expression profile (values and cross-correlations) of a group of WBC genes how can one predict their corresponding rank values and correlations in the OO set, and with what probability?

The impression given is that the broad expression of jun-1 is generated in an overlapping piecemeal fashion, different isoforms lacking specific distributions of functional significance and possibly expressed to some level in all cells.

However, given the broad patterns of co-expression and functional redundancy observed between co-members of various Sox families across the Sox phylogeny [ 27, 31, 32, 37- 49] 49], it is logical to ask whether such partial redundancy is a shared ancestral feature or the result of convergent evolution.