Given the alterations in the time-action profiles observed in our study, we speculate that postdinner hyperglycemia and increased risk of nocturnal hypoglycemia in the study by Nguyen et al. (5) were due, at least in part, to the mixed dose of aspart and detemir that was given at dinnertime.
Given the alteration in FO that corresponded to a gait alteration in the "decreased" group (6 12 mm), the accuracy for the preoperative planning of FO should ideally be about ± 3 mm.
Given the alterations in mitochondrial structure and biogenesis, we asked whether mitochondrial metabolism was disrupted in cumulus cells of diabetic mice.
Given the alterations in DNA methylation during the progression of prostate cancer [ 119], and the antagonistic relationship between DNA methylation and H2A.Z occupancy, it is not surprising that a few recent papers have also implicated the histone variant H2A.Z in this type of cancer [ 8, 12, 67, 68, 98].
Given the alterations in NRG1 and BDNF signaling pathways result in neuronal dysfunctions as well as the implication of NMDARs in neuroplasticity, our findings on the role of TrkB in NRG1-stimulated NR2B phosphorylation could be of relevance to many neurodevelopmental disorders, as NRG1 and BDNF signaling pathways have been implicated in autism and schizophrenia.
Given the alterations of global methylation in both viral infection and cancer, we examined genome-wide methylation levels in head and neck squamous cell carcinoma (HNSCC), a cancer causally associated with human papilloma virus (HPV).
Figure 2 gives the alteration of the average computational time (in seconds) gained by each term with N ranging from 50 to 400 when ((n,varepsilon)= 3,0.05)), by which one can observe that when (N>150) the running time increases rapidly, so the effect of variedness of the number of ratios on computational time is biggish.
Given that the alteration in greenhouse gas concentrations is the driver for the change, one expects the impacts to be highly dependent on the considered greenhouse gas scenario (GHS).
Given the observed alteration in hippocampal function in septic patients (Fig. 1), we postulated that the systemic inflammation, induced by LPS injection, would affect hippocampal synaptic plasticity, a phenomenon, reported to be critical for learning and memory [ 34].
Given that alterations in the Kirrel3 gene are associated with autism and intellectual disabilities, this work provides the first insight into cellular mechanisms that may underlie Kirrel3-dependent neurological disorders.
Given the marked alteration in the vascular system by LPS and systemic NO delivery tissue flow would be expected to be altered.
