In the Netherlands the Gross Motor Function Measure-66 (GMFM-66) and the original 88-item version (GMFM-88) are recommended to measure motor abilities on the activity level in children with CP [ 1], with GMFM-66 the more popular one given its reduced administration time.
Given its bioactive nature, administration of 15d-PGJ2 is likely to be associated with high toxicity and low bioavailability due to conjugation of 15d-PGJ2 to extracellular targets, including serum proteins [39].
In men with asymptomatic or minimally symptomatic metastatic CRPC, abiraterone is an attractive first-line option given its ease of administration and relatively low toxicity profile.
It was concluded that Raltitrexed might be favored over either 5-FU+LV combinations, given its ease of administration (one day every 3 weeks), reduced visits in the outpatient department and overall length of treatment and reduced non-hematologic toxicities, such as mucositis, diarrhea and hematologic toxicity, predominantly mild and uncomplicated neutropenia.
Moreover, Cpd #15 proved to be suitable for pulmonary topical administration given its sustained lung retention (t1/2 = 6.5 h) and high pulmonary levels (>100-fold higher than plasma levels) upon intratracheal administration in rats.
In the case of chronic therapies, the oral route is often the preferred route for drug administration given its acceptability and convenience.
But the one surprising move by the administration, given its oil-industry background, is its newfound interest in nuclear, once seen as the rival to oil and natural gas.
Moreover, organized labor would not have confidence in an arbitration process overseen by the Bush administration, given its intervention in airline negotiations and its bashing of public-sector unions in the debate over the Homeland Security legislation.
The Obama Administration, given its desire to support the democratic forces in Kiev and prevent Russia from squelching the reform movement, may well lean on the I.M.F. and the E.U. to move fast.
When Ethiopian troops first began a large-scale military offensive in Somalia late last year, officials in Washington denied that the Bush administration had given its tacit approval to the Ethiopian government.
