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The error function for a given combination of parameters can be thus defined as (9).
Results are checked experimentally and compared to the sound-pressure level; showing the noise emitted and the sound quality do not coincide for a given combination of parameters.
For a given combination of parameters, we denote the probability of surfing (conditioned on nonextinction of the total population) by psurf.
This means that for a given combination of parameters satisfying (10) we can have only one steady state (either x0 or x1).
We evaluated the methods using datasets simulated to represent different scenarios corresponding to a given combination of parameters of number of true hits, the amount of noise, the skewness of the data, the strength of chemotherapeutic drug effect, and the RNAi effect.
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Each panel depicts a threshold plane shaded according to the preferred strategy (according to the QALYs generated) for a given combination of parameter estimates.
Moreover, we are interested on the impact these parameters have from an architectural point of view, in order to determine up to which extent a given combination of these parameters leads to feasible or unfeasible hardware implementations.
For any given combination of simulation parameters, we ran 150 different simulations and finally averaged over all 150 different topologies.
We evaluated the methods using datasets simulated to present different scenarios corresponding to a given combination of the following parameters: sample size (5 or 10), proportion of differentially expressed genes (5% or 10%), ratio of up-regulated vs. down-regulated (1 1 or 3 1), lower bound of fold change (1.5 or 1.1), and lower bound of depth (5 or 1).
If none of the conditions in Equation 15 evaluates to true, no topological perturbation effect is defined for the given combination of k, i, t under parameter set J. We used the algorithm described above to detect TPEs of the ODE model constructed from the Endomesoderm Network.
If I had a quibble, it was with the driver profile selection system that will be fitted to most UK cars, which allows a driver to choose between four modes, Eco, Sport, Normal and Individual, each associated with a given combination of settings for engine mapping and other parameters.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com