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Two cohorts of patients were recruited, given an anticipated reduction in bone marrow reserve for patients who had undergone intensive chemotherapy Arm A – patients who relapsed after conventional therapy.
Given an anticipated debate over national identification cards, "we think that's good news," Mr. Rotenberg said.
Given an anticipated placebo ACR20 response rate of 20%, an odds ratio of 6 would translate into an ACR20 response rate of 60% for the ACZ885 treatment group.
Given an anticipated dropout level of 20% and the possible problems related to uneven randomisation (multicentre design with sites as one stratum), we decided to recruit 70 patients per group.
To detect a histological tumour clearance rate of 50% at 3 months, with a 5% significance level and 95% confidence, a sample size of 22 patients was necessary, given an anticipated dropout rate of 10% (http://www.nss.gov.au/nss/home.nsf/).nsf/
OpenEpi software was used to calculate a required sample size of 372, given an anticipated frequency of resistance to at least one antibiotic of 50%, with 95% confidence interval [ 14].
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On hills, or when adding power on corners, the engine gives an easy, anticipated response.
Then, on February 10th, two weeks after he was confirmed by the Senate — where thirty-four members voted against him, more than against any other Obama Cabinet nominee — he gave a highly anticipated speech laying out the Treasury Department's plan to nurse back to health the still fragile banking industry.
The potential to use biomarkers for identifying patients with the greatest chance of benefit and the lowest risk of experiencing adverse events in response to a given therapy is anticipated to have a major effect on both clinical practice (e.g., choice of treatment, dosing, or duration of treatment) and the development of new drugs and diagnostics [ 1, 2].
We prospectively planned an unbalanced recruitment ratio (1 2), given the anticipated smaller number of APC patients as compared with potential standard care patients.
Land area affected by combined stress is likely to increase given the anticipated climate changes [ 7].
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