Sentence examples for given alteration from inspiring English sources

In addition, it is not always possible to determine with precision the causal agent of any given alteration (Alberto et al. 2005).

Nonetheless, we will start with those which could have a general preventive effect, and continue with those which are more specific for a given alteration.

If a given alteration had neither created nor destroyed a restriction site, PCR amplification was carried out by PCR-mediated site-directed mutagenesis that artificially introduced a new restriction enzyme cleavage site (Supp. Table S2 [ Schwartz et al., 1991].

hiPSCs are easy to generate and present a good system for determining whether a given alteration is a new event or similar to the parental source cells that were used for their generation (Laurent et al., 2011).

Given alterations in the architecture and compliance of the carotid artery after a stent is deployed, subtleties in the performance and interpretation of carotid duplex ultrasonography must be appreciated.

Estimation of the true change in incidence is difficult from these data given alterations in population referral, potentially heightened clinician suspicion of NTM, and improved diagnostics, however our findings complement trends in other parts of the world that suggest increasing rates of NTM disease and species diversity [ 2, 3, 7].

It would be interesting to study whether the reduction in mtDNA gene copy could be reversed in aged mice given alterations to the rhTFAM dosing regimen, or whether this phenomenon reflects a fundamental change in rhTFAM effects on mtDNA replication in aged compared to young adult mice.

While some miRNAs are described as regulating developmental switches mediated through the repression of a single target, it is increasingly clear that the majority of miRNAs exert their effects through the modest reduction of a large number of targets which altogether give alterations in cellular phenotype [ 4, 6].

While few tissues can escape tumorigenesis, the vulnerability of different tissues to a given oncogenic alteration or several well-defined oncogenic alterations varies considerably.

Given the alteration in FO that corresponded to a gait alteration in the "decreased" group (6 12 mm), the accuracy for the preoperative planning of FO should ideally be about ± 3 mm.

The network displayed in Figure 1 clearly reveals the massive scale of influence that cigarette smoke, as an environmental variable, exerts over the lymphocyte transcriptome; however we are unable to determine which genes are directly influenced by smoke exposure, given that alteration of the expression level of one gene can alter the transcription of other genes in these networks.