Given the already known participation of FER in multiple hormone and defense signaling pathways, the FER-LLG1/LRE complex could equally be a surface co-regulator for multiple signals.
Second, when listeners encounter target sentences which do not convey any novelties but only previously 'given' already known information, the structuring of the speech input is driven by prosody again.
Some of the miRNAs identified by enrichment analysis are interesting candidates for further study given what is already known about their function.
A question is posed: is it good medical practice to continue to use a 'standard cuffed tube' given what is already known?
Fewer data are needed for subsequent downstream events, given what is already known on risks linking the pathway from early to late events, and with the presumption that downstream consequences are likely to occur when the upstream perturbation is observed.
Given what is already known about the characteristics of the epithelial calcium channels and calbindin D, it is a plausible hypothesis that CaT1 and calbindin D could work in tandem to maintain high rates of calcium absorption.
Given what is already known about the poor health practices and self-rated health of Aboriginal women, [ 7] there is a pressing need for more information on the health practices of this vulnerable subgroup.
We also propose that it may now be against good medical practice to continue to use a 'standard cuffed tube' given what is already known, and the weight of evidence supporting the use of newer tube designs.
Given what is already known about the coevolutionary history of the lice and their hosts, we can speculate that there are two mutually exclusive explanations that can account for the current distribution of Pediculus and Pthirus.
The observed downregulation in 5 7 mm follicles from broiler breeders is in marked contrast to the layers, which would support the hypothesis of potential dysregulation of part of the steroid-based feedback mechanisms, given what is already known of the PDGFR family in other species.
Given what is already known about gene duplications in angiosperm history [e.g. [ 41- 43]], the BLAST based measures of overlap are almost certainly underestimates of cross-taxon sampling of orthologous gene sets (including co-orthologs [ 44]) represented in our EST sets.
