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When given alone to the saline-treated group, EMQMCM indicated anxiolytic-like effect.
Neither l-KYN, nor PROB, or their combination, produced major alterations in motor function when given alone to rats.
Both these drugs when given alone to non-stressed animals did not alter basal levels of antioxidant defense components and oxidative stress markers significantly.
In cycle 2, olaparib was administered on days 2 8 to permit the pharmacokinetics of dacarbazine given alone to be determined.
GM-CSF was given alone to six patients during the first part of the study to determine a dose that would produce a peripheral leucocyte count (WCC) greater than or equal to 50 X 10 9) 1(-1) and was initially given at 3 micrograms kg-1 day-1 and escalated to 10 micrograms kg-1 day-1 after 10 days.
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Anyway, some patients responded completely to caffeine given alone at bedtime.
In the present study, BMP7 (100 ng/ml), when given alone, led to a 190% increase in PG production.
In the early 1990s, evidence of superior efficacy over either compound given alone led to the widespread use in the United States of combined treatment with phentermine and fenfluramine (Weintraub et al., 1992).
Another treatment, estrogen alone — given only to women who had surgery to remove the uterus — also increased the risk of blood clots, strokes, gallstones and urinary incontinence.
While most of the available data deals with tamoxifen given alone, it appears to have a similar beneficial effect when added to chemotherapy in the premenopausal adjuvant setting.
The results of this trial were surprising because previous studies showed that these vaccines, given alone, were unable to elicit consistent T cell responses [6] or protective antibody responses [7], [8].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com