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Compounds having AlogP between 3.7 and 34 are given a high probability of being toxic by the model, the probability of being toxic increases at the higher end of the range.
Their stance is simple: since the test is now non-invasive, more women will opt to have it, which means more women will be given a "high" probability of having a child with DS, which means more women may take the decision to terminate their pregnancy.
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Higher molecular weights give a high probability of toxicity.
This is due to a highly efficient charge extraction, as all generated charges are very close to the electrodes, giving a high probability of being collected before recombining.
Genotype determination requires multiple reads overlapping a single position to give a high probability of observing both alleles at a potential heterozygous site.
Increasing the population size to give a high probability of recovering a plant with advantageous alleles at, say, 26 loci ought to increase P1 over having a smaller population size where 25 can be expected.
In conclusion, the evidence level remained unclear: formally, multiple RCTs have shown positive effects on (different) clinical outcomes of diuretics, but the methodological quality of the meta-analyses (and the RCTs themselves) give a high probability of biased results.
With this escalation plan, all women in the pilot study had first menses by 12 weeks, giving a high probability of observing two normal menstrual periods by 16 weeks.
The only clinical factor associated consistently with improvement in SWN scores was the SWN score at baseline (lower subjective well-being giving a higher probability of improvement).
The mechanism gave a higher probability of missing sex with increasing weight, e.g. the probability of missing information about sex was 27% for an individual weighing 40 kg and 83% for an individual weighing 145 kg.
Although this would minimize our type I error rate, it would have depleted our statistical power, thus giving a higher probability of type II error (that is, the probability of rejecting an association that actually exists).
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