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Given a high number of roads, the algorithm runs for 100 iterations to find 100 flagged roads.
Given a high number of potential CSPs and controls for each CSP creating this mapping would require significant manual work.
These improvements focus on lowering the number of false positives due to added variance or systematic biases, since the utility of pooling-based approaches will be based on how one can detect association signals given a high number of false positives.
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A reason for this is that in bigger herds, the risk of transmission is higher given a higher number of "infectious" and "susceptible" animals, offering increased chances of more effective contacts per unit of time.
The Tuberculin test (TT) has been used up until now for LTBI screening, but gives a high number of false positives, especially in patients vaccinated with BCG.
The scientists gave a high number of MRSA bacteria to the mice, eliciting an infection.
At the other extreme, sensitivity was generally high for HapBlock, but this method had a poor specificity thus giving a high number of false positives.
Before making the library, a number of test-ligations should be performed to ensure that optimal conditions are used, i.e. that the ratio of vector to DNA fragments gives a high number of clones with an inserted DNA fragment.
They recorded higher sensitivity levels for the EIA (87.1%) than those recorded in this study but suggest that the EIA has a low reproducibility level and could give a high number of false-negative results.
Note that the combinatorial effect of the repeats (that is, that several occurrences of a domain in a row give a high number of occurrences and a very low number of neighbours) have been accounted for as described in the previous section.
Despite the sample obtained from DB110 strain grown at 0.1 MPa gave a high number of reads, the number of those having a single alignment is quite low; we hypothesize this could be due to a lower efficiency in rRNA depletion during the preparation of this sample.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com