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Together, in vitro and in vivo data give proof of concept of higher therapeutic activity of tumor-targeted scFv scTRAIL molecules.
(#1020, 56, W) Besides giving additional support to the findings of the first (hypothetical) stage of our study, the results reported here give proof of concept that HIV-uninfected MSM from diverse ethnic backgrounds who never or rarely use condoms and have intercourse with multiple partners understand the limitations of HT and are willing and able to use HT to screen partners.
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These results give proof-of-concept that progenitor cell types can be produced in sufficient quantities for use in canine therapeutic cell transplantation for SCI in veterinary medicine.
We have given proof-of-concept for this new approach with mimotope A12.2 and have brought the finding full-circle by demonstrating differential recognition of native versus denatured HIV-C gp160 by phage affinity-purified rhesus monkey abs.
This study gives proof-of-concept of efficacy, tolerability and clinical relevance of the combined gene/cell therapies proposed here, which may constitute a feasible and effective therapeutic opportunity for children affected by GLD.
The present proof-of-concept study gives efficacy and safety arguments warranting the further clinical evaluation of the H-1PV/VPA combination for use against life-threatening cancers.
The analysis of gene and miRNAs expression profiles gave a proof-of-concept of the scalable character of biological regulation circuits.
By analyzing both protein coding genes (PCGs) and miRNAs expression during hematopoiesis, we gave a proof-of-concept of this attractor-like dynamics and were able to characterize the coordinated and scalable character of cell population behaviour in both mRNAs and miRNAs spaces.
We stress once again that the aim of this work is to give a proof of concept that both node mobility and node cooperation can help thwarting the node capture attack.
The purpose of presenting them is twofold: (1) to highlight the advantage of the proposed initial condition concept especially on those machines and (2) to give a proof of concept mapping of this fast evolution on two totally differently organized (virtual and physical) many-core machines.
Moreover, we use retinal SD to give a proof of concept of the existence of this instability point and describe how cortical susceptibility to SD must be adjusted for migraine drug testing.
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