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"give it up" is correct and usable in written English.
You can use it to tell someone to stop doing something, or to admit defeat or give in to a situation. For example, "We've been arguing for hours, let's just both give it up and agree to disagree."
Dictionary
give it up
verb
To welcome onto a stage; to cheer; to applaud.
Exact(47)
Give it up, Blanche!
Give it up, Clark!
Would he give it up?
"Can I give it up?
"Don't give it up".
Why would they give it up now?
Similar(13)
But giving it up?
He gives it up.
She wordlessly gives it up.
You're giving it up.
(She gave it up a month ago).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com