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The response can be especially harsh when the play isn't reconceived for London, which is just one reason why Shanley was wise to give Doubt to the Tricycle's artistic director, Nicolas Kent, with leading lady Dearbhla Molloy playing the part of a stern-faced scold of a nun that Meryl Streep will take in the forthcoming film version of the play.
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It keeps giving doubt, grief and anxiety forever.
Given doubts over his leadership and Egypt's other troubles, this is an alarming prospect.
They also questioned why the administration had not demanded an accurate analysis of the flow of leaking oil, given doubts about BP's initial estimates.
She twice pressed Green on whether walking away from negotiations without a deal, as threatened by May, was still possible given doubts expressed by the chancellor, Philip Hammond.
Given doubts over CCS and the limited number of high-efficiency coal power plants, coal's role on a climate-aware planet appears precarious.
Saudi spare capacity is the "global cushion" for oil supply, and even the possibility that it could drop to 1.5 million barrels per day or below jolts markets and increases the barrel price, especially given doubts about Saudi capacity.
The answer Platt gives us is the same answer he gives doubting directors: We're in PCs because we have to be.
While he supported the government's de-carbonisation strategy, he said setting a specific target for 2030 now - as the Lib Dems want - would be "unwise" given doubts about the capacity of carbon capture and storage technology.
Williams goes on to point out that Obama's decision will likely excite young voters and base traditionalists, while giving doubts to older voters and voters in places like Virginia.
We also varied this value over a wide range, given doubts about the adequacy of many poorer countries' cold chain infrastructure to accommodate the added volume of a bulky new oral vaccine.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com