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Microarray data is also utilized to give annotation of REGs, that have been predicted as cis-regulatory elements dependent of promoter position in our previous analysis.
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Only GOPred was able to give annotations for RGL4 such as guanyl-nucleotide exchange factor, small GTPase binding that were similar to those reported in the literature.
It is also important to note that we do not merely give annotations but also provide a measure for each functional class that states how probable it is that the query protein is a member of that class.
The estimated value is the proportion of a given annotation class seen in the set of hit SNPs divided by the proportion seen in the set of non-hit SNPs.
Clicking on a GO term allows browsing all entries sharing a given annotation.
We define a subclass with more than 75% conservation of a given annotation as PSFRS.
Count: Number of genes differentially expressed between t-AML-resistant and -susceptible inbred strains of mice with given annotation.
Necessary gene annotation is distributed across numerous individual sources, hampering integration for given annotation beyond the challenge of adding annotation to novel species identified in metagenomics.
Thus, for a given annotation term for a given transcript set, we can see the relative breakdown of annotations obtained when using the other transcript set.
This workflow can be adapted for use with any models, annotation sources, and additional reaction sets given annotation availability and user preferences.
These analyses measure the consistency of significance statistics (P value) and gene expression variation (fold-change) over a gene set corresponding to a given annotation term.
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