Sentence examples for give a high binding from inspiring English sources

Magnetite graphene composite adsorbent with a particle size of ~10 nm was reported to give a high binding capacity for As III) and As V) [112].

Compounds 4 and 5 are close analogues, differing only in the position of a methyl group, and both give a high binding response to sGC in the SPR assay, similar to YC-1 (2) itself.

Radiotracer design for TSPO for the brain aims to achieve optimal passive diffusion across the BBB without impediment by efflux transporters (E.T). to give a high specific binding (indicated by red circles).

[C] 7– 9 were each easily prepared and readily entered monkey brain to give a high proportion of specific binding to brain TSPO.

Each radioligand was readily prepared by C-methylation of an N-desmethyl precursor and was found to give a high proportion of TSPO-specific binding in monkey brain.

This could give a higher lift.

Given previous research that demonstrates a high binding affinity of estrogen-related receptor-γ (ERRγ) to BPA [ EHP 116 32 38 (2008)], the researchers speculate that ERRγ, expressed by both cell lines in their study, is the most likely target for BPA binding.

Basically, we feel that the previous studies had technical flaws and, in both cases, binding was done under conditions that would be predicted to favor protein oligomerization which would give an artificially higher binding affinity.

The TNF-308A allele leads to high binding affinity of nuclear factors to the TNF promoter and gives a high level of gene transcription (Kroeger et al. 1997).

Hence, the positions with a higher binding energy given by IC (and also a lower binding energy) are usually clustered as local information blocks in the PFM model of functional motifs [ 30].

Even in the presence of quinidine and ketoconazole, which are inhibitors of drug-metabolizing CYP2D6 and CYP3A4, respectively, 29 39% of compound 53 was metabolized in 20 min. Given high binding to plasma proteins (>99.8%) and strong inhibition of the hERG ion channel (94% at 10 μM), 53 has poor predicted prognosis for bioavailability and cardiotoxicity.